Manganese is an essential nutrient that plays a role in many biological processes, including metabolism, bone development, and wound healing. It is found in a variety of foods, including whole grains, nuts, and leafy green vegetables.

While manganese is important for human health, exposure to high levels of manganese can be toxic and cause neurological symptoms such as tremors, difficulty walking, and cognitive impairment. Vulnerable groups such as infants, the elderly, and those with liver disease may be more sensitive to the effects of manganese toxicity.

The recommended dietary allowance (RDA) for manganese varies depending on age and sex, but ranges from 1.2 to 2.3 mg/day for adults. Most people in the United States consume adequate amounts of manganese through their diet, and supplementation is generally not necessary. However, excessive intake of manganese from supplements or fortified foods can also be harmful and cause toxicity.